Those with a particularly keen eye for puzzles and challenges will spend no time at all trying to solve the mysterious ‘Final Puzzle’ challenge in Resident Evil Requiem, which consists of a bunch of obtuse clues and steps that can be incredibly easy to miss.
Finding these hints and ultimately piecing them together throughout the game is no easy feat by any means, and that’s why – at the time of writing – we still haven’t been able to solve it. Below, we’ve detailed all of the Final Puzzle clues, hints, and steps we’ve found so far in the hopes that perhaps the person reading this might be able to do something with them.
If you do solve the Final Puzzle in Resident Evil Requiem using these clues and hints, please let us know!
Also, here’s your spoiler warning for the following page! The Final Puzzle’s clues span most of Requiem’s story, so be careful reading ahead if you’ve not yet finished your first playthrough.
On this page:
Resident Evil Requiem Final Puzzle explained
The Final Puzzle is one of many challenges listed in the Resident Evil Requiem’s ‘Challenges’ menu. It’s worth 20,000 CP once it’s been completed, and your only clue for this particular challenge is as follows:
“Let the sweet pair hear the voice.”
Interpret that however you please, because as it stands, we have tried and tested a lot of possible solutions and currently don’t have the foggiest idea what this could mean. The key things to note here are the mentions of “sweet pair” and “voice”.
Now, “sweet pair” could be referring to the likes of Grace and Leon, whom the game centers around, or even Grace and Emily. Alternatively, perhaps it’s referring to Emily and The Girl (who we can only assume was possibly in the cell opposite Emily’s in Rhodes Hill Care Center). There’s even two singers featured in Rhodes Hill…
As for what the “voice” refers to, we’re really not quite sure.
Resident Evil Requiem Final Puzzle hints and clues
Throughout the rest of this page, we’ve detailed the clues we’ve found so far (or at least, what we suspect are clues) and how they are related to one another. We also currently suspect that without prior knowledge of the puzzle, it can only be completed in New Game Plus.
Final Puzzle Clue #1, Severed Hand
The first clue that points to the Final Puzzle in Resident Evil Requiem is The Girl’s Severed Hand.
Once you escape from the Basement beneath Rhodes Hill Care Center via the elevator, you’ll actually shut the elevator on The Girl, forcibly dismembering her hand. Gross. What’s even more gross is you can pick up this Severed Hand and add it to your inventory.
Now, as you continue exploring Rhodes Hill Care Center and run into the Laser Microscopes (which allow you to solve puzzles to unlock new recipes), it turns out you can actually place the Severed Hand into one of the Laser Microscopes.
Upon doing so, you’ll need to solve one of the minor Laser Microscope puzzles as per usual, but rather than unlocking new recipes for your efforts, something else appears…
You are presented with the message that reads “Let’s play” alongside the following code:
‘GGC AAG AUA ACG UGU CAU’
What this code means is yet to be revealed, but the following clues help us along a little.
Final Puzzle Clue #2, Lead Researcher’s Puzzle Box
After successfully opening the Lead Researcher’s Puzzle Box in Rhodes Hill Care Center (which contained the Star Quartz and a Notebook) and scanning the Severed Hand at a Laser Microscope, you are able to input another code despite the Puzzle Box already being unlocked.
With this in mind, we can only assume that the code from the Severed Hand can be translated into a code involving the Sun, Moon, and Star symbols. More on this shortly.
Final Puzzle Clue #3, Laser Microscope
If you look at the side of the Laser Microscope machine in the Blood Lab in Rhodes Hill Care Center, there’s a label on the side of this machine that says the following:
‘G = 150000000’
Now, hear me out (and thanks is owed to IGN for this!), but given the assumption that the code from the Severed Hand could correlate with the Puzzle Box’s Sun, Moon, and Star symbols, folk have done some sleuthing as to how these numbers correlate with those three things.
It just so turns out that the Sun is 150 million miles away from Earth and using that logic, G = Sun.
Final Puzzle Clue #4, Hourglass
Once you make your escape from Rhodes Hill Care Center and begin looking for the Helicopter Key, you’ll quickly run into an Hourglass you can unscrew from the desk of the VIP Suite.
If you rotate this hourglass and allow it to drain, a code is revealed that reads:
‘U = 380,000’
Again, if we’re trying to relate these numbers to real-life facts related to the Sun, Moon, and Stars, it just so happens that the Moon is 380,000 kilometers away from Earth.
Using that logic, this means that U = Moon. We just need to work out what ‘C’ and ‘A’ mean next.
Final Puzzle Clue #5, Grace Ashcroft Blood Analysis Report
While exploring the facility beneath the Helipad in Rhodes Hill Care Center’s grounds (this is where you find the Helicopter Key), you can find a document – Grace Ashcroft Blood Analysis Report – on one of the desks.
Careful perusal of this document reveals that ‘C = 4.2 ly’, and of course, it just so happens that the closest Star to Earth is 4.2 light years away.
This means that C = Star.
Final Puzzle Clue #6, Toy Uncle Bobblehead
While playing as Leon following the Tyrant boss fight, there’s a caged off sports court where you’ll find a Toy Uncle Bobblehead that you can kick around.
There’s also a basketball hoop lying on the ground in this sports court. If you successfully kick the Uncle Toy Bobblehead through the hoop, you can then interact with the hoop to receive a message: “There’s no time for playing around.”
After this, head into the back of Kendo’s Gun Shop, where you’ll find the torso of the Toy Uncle Bobblehead. Interact with it and you’ll be told to ‘Just ignore A’ which we can only assume means we can remove A from the Severed Hand code.
This changes the earlier Severed Hand code from ‘GGC AAG AUA ACG UGU CAU’ to the following:
‘GGC GUC GUG UCU’
Final Puzzle Clue #7, Returning to the Lead Researcher’s Puzzle Box
After discovering all of the above in one playthrough, you technically won’t be able to do the following step until you start a second playthrough.
This step involves returning to the Lead Researcher’s Puzzle Box after it has been unlocked, translating the Severed Hand code into Sun, Moon, and Star symbols, and then inputting said code.
The code is as follows:
Sun, Sun, Star,
Sun, Moon, Star,
Sun, Moon, Sun,
Moon, Star, Moon
Once you’ve done that, you’ll hear the sound of some childlike laughter.
While this cracks the code of the Severed Hand, this doesn’t mark the Final Puzzle challenge as complete, nor does it unlock the associated achievement for it. This can only mean one of two things:
- The above code is a ruse and we’re being laughed at, meaning there perhaps is another way of cracking the above code. Or maybe there are additional codes…
- There’s additional steps during or steps after the laughter from the Puzzle Box that we’re missing. Notably, the Severed Hand and Victor Gideon’s Notebook remain in your inventory long after leaving Rhodes Hill, so perhaps there is somewhere else to use these items.
Curiously, this puzzle does also bear some similarities to one featured in the demo for Resident Evil 7: Biohazard and I wonder if that has anything to do with things.
Hopefully, using the above information – which was kindly put together by reviewers and guides writers across our network – you might be able to figure something additional out so the community can finally solve this puzzle.
If you find out anything more about the Final Puzzle challenge that could help the community with solving it, please do let us know!
For more on Resident Evil Requiem, take a look at our walkthrough, guides, and tips and tricks.