The Spurs improved to 46-17 and are now 2.5 games behind Western Conference leaders the Oklahoma City Thunder.
Slovenian star Luka Doncic scored 44 points as the Los Angeles Lakers won 128-117 at home to the Indiana Pacers.
The Lakers were without LeBron James (elbow, foot) as Doncic scored his 10th 40-point haul of the season, breaking a tie with Minnesota’s Anthony Edwards for the most this season.
London-born forward OG Anunoby scored a season-high 34 points as the New York Knicks won 142-103 at the Denver Nuggets.
Denver’s star guard Jamal Murray missed the second half after rolling his left ankle when he stepped on team-mate Nikola Jokic’s foot.
The Knicks remain third in the Eastern Conference behind the second-placed Boston Celtics, who won 120-100 at home to the Dallas Mavericks as Jayson Tatum played his first game of the season.
The six-time All Star scored 15 points from 27 minutes of action on his return after suffering a ruptured Achilles during last season’s play-offs.